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Research Support
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Grant #test
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Publications
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Other Publications
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Dahms, T. E. S., Sainz, G., Giroux, E. L., Caperelli, C. A., and Smith, J. L.
(2005).
The Apo and Ternary Complex Structures of a Chemotherapeutic Target: Human Glycinamide Ribonucleotide Transformylase.
Biochemistry
,44
(9841),
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Baird-Titus, J. M., Clark-Baldwin, K., Dave, V., Caperelli, C. A., Ma, J., and Rance, M.
(2006).
The Solution Structure of the Native K50 Bicoid Homeodomain Bound to the Concensus TAATCC DNA-binding Site.
J. Mol. Biol
,356
(1137),
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Positions and Work Experience
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09-1995
to Present
Professor, Division of Pharmaceutical Sciences
University of Cincinnati, College of Pharmacy
Cincinnati, OH
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08-1987
-09-1995
Associate Professor, Division of Pharmacology & Medicinal Chemistry
Univ. Cincinnati College of Pharmacy
Cincinnati, OH
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01-1986
-07-1987
Clinical Member, Division of NMR,
Fox Chase Cancer Center
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09-1979
-01-1986
Assistant Professor, Department of Chemistry,
New York Univ.
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04-1978
-08-1979
Postdoctoral Fellow, Department of Chemistry
Penn State Univ.
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04-1976
-03-1978
Damon Runyon-Walter Winchell Cancer Fund Fellow
Department of Chemistry
Penn State Univ.
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03-1975
-03-1976
Postdoctoral Fellow, Department of Chemistry
Penn State Univ.
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09-1970
-02-1975
Graduate Student, Department of Chemistry
Johns Hopkins Univ.
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Education
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Institution:Pennsylvania State Univ.
BS
03-1970
Chemistry
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Institution:Johns Hopkins Univ.
Ph.D.
03-1975
Physical Organic Chemistry
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Institution:Pennsylvania State Univ.
Postdoctoral
08-1979
Biochemistry/Enzymology
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Keywords
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Enzyme Mechanisms,Enzyme Inhibition,Purine Biosynthesis,Nucleotide Metabolism,Folate Enzymes,Folate Metabolism,Multifunctional Enzymes
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Research and Practice Interests
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Bioorganic chemistry, mechanistic enzymology of purine biosynthesis and folate metabolism, protein-protein and protein-nucleic acid interactions, enzyme structure/function
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Community of Science Research Interests
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Purine biosynthesis and the enzymes which catalyze the conversions of the pathway.
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